The vaccine technology could be used in vaccines against SARS-CoV-2 and beyond Panelists gave high marks for recently released early results of Phase 3 vaccine trials, saying the work has been conducted to high scientific standards, and the efficacy rates of 90 percent for the preventative from Pfizer, which applied for an FDA emergency use authorization on Friday, and 94.5 percent from one by Moderna Inc. are not only encouraging, but better than they had hoped. (AstraZeneca also reported early numbers on Monday, with effectiveness of up to 90 percent, depending on dosage.) That, together with reports of relatively minor side effects, makes experts optimistic that these and other vaccines may represent a light at the end of the pandemic tunnel.But that light is still a way off, panelists cautioned. The Pfizer and Moderna vaccines have a couple of drawbacks: Both have to be stored in cold temperatures — the Pfizer vaccine at minus 70 degrees Fahrenheit, and Moderna’s at minus 20 — and both also require two doses to be effective. Those characteristics not only mean that regions with the equipment to handle the storage demands — urban areas — are likelier to get the vaccines first, but also that any vaccine education campaign should emphasize that people can’t abandon public health precautions after the first shot because they won’t be immune until shortly after their second shot, some five or six weeks later. Complicating all of that, Walensky said, is the fact that 25 percent of Americans don’t have a primary care doctor, the normal administrant of things like vaccinations.“The day you get your vaccine is not the day you take off your mask,” Walensky said. “We’ll be in a much better place once the population is vaccinated, but we won’t be without masks for a while.”Vaccines being tested by AstraZeneca and Johnson & Johnson were created by more traditional means than the messenger RNA preventatives of Pfizer and Moderna. Depending on the final outcome of those still-ongoing Phase 3 trials, those treatments will likely be more forgiving with regard to storage and have differing efficacy and side effects, which may make them better suited to distribution in parts of the country distant from minus 70-degree freezers.Walensky and Fortune were joined by Barry Bloom, the Joan L. and Julius H. Jacobson Research Professor of Public Health, and epidemiology Professor Marc Lipsitch, who heads the Chan School’s Center for Communicable Disease Dynamics, at a Facebook Live event on Friday that was sponsored by The Forum at Harvard T.H. Chan School of Public Health and NPR.With cases and hospitalizations soaring nationally, and a corresponding rise in deaths likely not far behind, Lipsitch said it’s important that we not let the prospects of a vaccine cause us to ease up on the public health steps we know will work and that, even now, can still make a difference in the course of the pandemic if adopted more widely. “The science has come through for us. The real challenge now is to get public acceptance of the vaccines that will be forthcoming.” — Barry Bloom, the Joan L. and Julius H. Jacobson Research Professor of Public Health ‘A terrific first start’ “The future is in our hands,” Lipsitch said.While much has been made of the potential problem of vaccine reluctance, Lipsitch said he thinks it may not be as high a hurdle as some surveys have shown. People may answer a hypothetical question one way but behave differently when friends and neighbors are getting vaccinated and resuming a semblance of normal behavior, he said.It is, however, important that education campaigns include the fact that side effects from the vaccines are possible, panelists said. While the clinical trials so far haven’t found problems severe enough to call their safety into question, some who received the Moderna and Pfizer vaccines experienced soreness at the injection site, aching muscles, and fatigue that faded after a few days. It’s important, Lipsitch and Fortune said, that people are aware of that ahead of time, so resulting alarm doesn’t feed any anti-vaccine sentiment.“There’s a tendency just to say, ‘Vaccines are safe. It’s no problem,’ and people don’t trust that if their lived experience is different,” Fortune said. “If we don’t have those conversations, then I think our credibility is eroded.” A public-relations campaign to build trust in COVID vaccine? Skeptics’ refusal may be big hurdle to ending pandemic, returning to normal Experts are working out a broad strategy to vaccinate Americans, with an eventual plan likely to prioritize health care and essential workers, as well as the vulnerable elderly and those with risk factors for severe disease.Even with a strategy in place, however, the devil will very likely be in the myriad details if it is to be a success, experts said. For example, even if initial distribution is limited just to health care workers alone, that’s not an inconsiderable cohort: There are 20 million of them. If you want to add essential workers that’s another 60 million. In addition, even minor side effects that mirror the disease will sideline those who have to report that they are symptom-free before coming to work each day. That means, for example, a campaign that inoculates an entire intensive care unit’s workforce on the same day could have disastrous consequences if a significant number report symptoms the next day and can’t come to work.Those examples, offered by Rochelle Walensky, chief of Massachusetts General Hospital’s Division of Infectious Diseases and a professor at Harvard Medical School, represent just some of the potential hurdles to be overcome in a vaccine rollout that promises to be not only vast, but also vastly complicated. However, experts said Friday that the vaccine rollout presents another opportunity to get the fight against the coronavirus right, despite the nation’s failure to take steps needed to prevent infection on a massive scale.“I am struck by the challenges that we have ahead of us in thinking about rollout,” said Sarah Fortune, chair of the Department of Immunology and Infectious Diseases at the Harvard T.H. Chan School of Public Health, who appeared on a recent online panel with Walensky. “We, as a society, have not done necessarily the best job in terms of getting our prevention measures in place, our response measures in place, and now we face an enormous challenge but an enormous opportunity to get this next phase right.” “The day you get your vaccine is not the day you take off your mask.” — Rochelle Walensky, chief of Mass. General’s Division of Infectious Diseases Fortune said it’s important to talk not only about common side effects but also the potential for very, very rare side effects, such as neurological issues that caused some trials to be paused. Without transparency and openness, Fortune said, the vaccination campaign’s credibility will be damaged.“If we’re not honest about that, the public can sniff those out and the credibility of the vaccination effort is undermined,” Fortune said.After the vaccines are deployed, the studies won’t stop, Bloom said. Instead they’ll enter what he termed “Phase 4” — post-approval monitoring for rare side effects in a much broader population over a longer time than the original trials. They’ll also look for clues to other unanswered questions, primarily whether the vaccines not only prevent illness, but also prevent infection, and how long vaccine immunity lasts. Additional outstanding questions include how well the vaccine works in the elderly — the preliminary results released recently didn’t include data for subgroups — and children, on whom it is unethical, Bloom said, to even begin a trial until safety data is confirmed in adults.“It’s not all over when the government issues an emergency use,” Bloom said. “The science has come through for us. The real challenge now is to get public acceptance of the vaccines that will be forthcoming.” Related Why isn’t the right more afraid of COVID-19? Chan School’s Barry Bloom puts vaccine news into context Rejecting science and expertise, as the president urges, has become a reflection of loyalty, analysts say Putting a crown on OMNIVAX
Notices: The Florida Bar; JNCs Third DCA JNC seeks applicants The Third District Court of Appeal Judicial Nominating Commission is now accepting applications for a vacancy on the court.All persons who desire to be considered must submit a background statement in substantial compliance with The Florida Bar application. All applicants must also submit waivers of confidentiality of all materials necessary to adequately investigate each applicant.Applications may be requested from the office of the Hector J. Lombana, JNC Chair, Gamba & Lombana, P.A., 2701 Ponce de Leon Boulevard, Mezzanine, Coral Gables 33134, phone (305) 448-4010, fax (305) 448-9891, e-mail [email protected], Monday through Friday between 9 a.m. and 5 p.m. Applications also may be downloaded from The Florida Bar’s Web site.All applications must be submitted in the form of an original with nine copies and must be received by Lombana no later than 5:30 p.m. September 30. Workers’ Comp JNC needs new members The Statewide Nominating Commission for Judges of Compensation Claims is seeking applicants for the following vacancies on the commission: One resident each from the territorial jurisdictions of the First, Third, and Fifth DCAs to serve terms commencing immediately and expiring on June 30, 2005.Persons to fill these vacancies will be selected and appointed by a majority vote of The Florida Bar and governor-appointed members of the commission. No attorney who appears before any judge of compensation claims more than four times a year is eligible to serve on the commission, pursuant to F.S. §440.45(2)(b). Commissioners are also not eligible for state judicial vacancies filled by the JNC on which they sit for two years following the expiration of their term and are subject to Florida financial disclosure laws. Meetings and deliberations are open to the public.Those interested may contact G. Bart Billbrough, Chair, Suite 902, 2600 Douglas Rd., Coral Gables 33134, to obtain the proper application. Completed applications must be returned to Billbrough no later than the close of business October 11. Resumes will not be accepted in lieu of the required application. Board to fill workers’ comp JNC vacancy The Board of Governors is seeking applicants for the following vacancy:• Statewide Nominating Commission for Compensation Claims Judges: One attorney from the territorial jurisdiction of the Fifth DCA (which encompasses the Fifth, Seventh, Ninth, and 18th circuits) to serve an interim vacancy commencing immediately and expiring July 1, 2003. All applicants must be members of the Bar who are engaged in the practice of law. No attorney who appears before any judge of compensation claims more than four times a year is eligible to serve on the commission, pursuant to F.S. §440.45(2)(b). Commissioners are also not eligible for state judicial vacancies filled by the JNC on which they sit for two years following the expiration of their term. Commissioners are subject to Florida financial disclosure laws. Meetings and deliberations are open to the public.Persons interested in applying for the JNC vacancy should contact The Florida Bar at (850)561-5600, ext. 6802, to obtain the proper application form. Applications may also be obtained by writing the Executive Director, The Florida Bar, 651 E. Jefferson Street, Tallahassee 32399-2300.Completed applications must be received no later than the close of business Tuesday, September 17. Resumes will not be accepted in lieu of the required application. Morrison petitions for reinstatement Pursuant to Rule 3-7.10, Robert Wayne Morrison has petitioned the Supreme Court for Bar reinstatement.Pursuant to an order from the Supreme Court, Morrison was suspended for six months, effective September 1, 2001, for pleading no contest to charges of possession of cocaine and resisting an officer without violence, for pleading no contest to charges of reckless driving and failure to wear a seat belt, and for pleading no contest to charges of battery (domestic violence).Any persons having knowledge bearing upon Morrison’s fitness or qualifications to resume the practice of law should contact Frances R. Brown-Lewis, The Florida Bar, 1200 Edgewater Dr., Orlando 32804-6314, phone (407) 425-5424. Proposed changes to FAR/BAR Contrac t The Realtor-Attorney Joint Committee is now soliciting suggestions on improving the FAR/BAR Contract, in an effort to update the contract and to make it more user-friendly.The committee also would like comments on making the contract an “as is” contract with standards “D” and “N” being removed from the contract for inclusion in the rider.Comments on the proposed changes to the FAR/BAR Contract may be sent to Janet Valentine, at [email protected], fax (407) 438-1411, or mail them to Florida Association of Realtors, Janet Valentine, P. O. Box 725025, Orlando 32872-5025.The deadline for making any comments is September 30. U.S. 11th Circuit to fill information tech position The Circuit Executive’s Office for the 11th Circuit, United States Court of Appeals is now accepting applications for an assistant circuit executive for information technology.Applications are being accepted through September 20, or until the position is filled.An application letter with resume should be submitted to: Cheryl Vessels, Human Resources Manager, United States 11th Judicial Circuit, 56 Forsyth Street, NW, Atlanta, GA 30303.The person selected for the position will be required to undergo a background investigation. YLD seeks service award nominations The Young Lawyers Division is now accepting nominations for its YLD Legal Aid/Public Service Award.The award recolonizes public service of legal aid preformed by a public sector lawyer who provides outstanding contributions to those in need of free legal services.For more information or to make a nomination contact Austin Newberry, YLD administrator, at 651 E. Jefferson Street, Tallahassee 32399-2300 or (850) 561- 5624 or [email protected] The deadline for receipt of nominations is December 1. September 15, 2002 Regular News
Combined soybean exports from Brazil and the U.S. are down 7.8% in the first eight months of this year, as the main Brazilian soybean export season disappointed, according to BIMCO.The fall in volumes from the two countries has also led to an 8.5% drop from last year in the tonne mile demand generated by the two dominant soybean exporters.In particular falling exports from Brazil have hurt the shipping industry, with accumulated soybean exports from Brazil in the first eight months of this year 7.8 million tonnes lower than the first eight months of 2018, BIMCO explained. This has resulted in tonne mile demand from Brazilian exports falling by 12.9% or 83.7 billion tonne miles.U.S. soybean exports in August 2019 were the highest they have ever been in the month of August reaching 4.5 million tonnes, 1.4 million tonnes higher than exports in August 2018. However, this growth does not make up for the loss in tonne mile demand from Brazil, which exports higher volumes of soybeans than the U.S.”The coming months will determine the outcome of the year for seaborne U.S. soybean exports, with early signs that exports since September 1 seem to be following the usual pattern of increasing through September ahead of a peak in late October and November. This would be good news for the shipping industry, but it is currently too early to call the season a success,” Peter Sand, BIMCO’s Chief Shipping Analyst, said.
read also:Wenger turns down Barca job after talks to replace Setien “I work in FIFA and I work very hard and I didn’t speak to anybody. I don’t know where that news came from.” “Between a massive club like Barcelona and the national team, you understand his decision,” Wenger added on Koeman possibly going to Barcelona. “He is 57-years-old, he has never worked in a massive foreign club and this is the opportunity of his life for him to take the job.” FacebookTwitterWhatsAppEmail分享 Loading… Former Arsenal manager, Arsene Wenger, has rejected claims he is about to manage the Dutch national team. The Netherlands may have to find a new coach as Ronald Koeman is set to sign for Barcelona for the coming season. A report from Fox Sports linked Wenger to the job, but Wenger has told beIN Sport that he remains committed to fulfilling his role as FIFA’s Chief of Global Football Development. “I believe there were some reports saying that I offered my availability to take the job, but I am not available,” Wenger said.Advertisement Promoted Content8 Things To Expect If An Asteroid Hits Our PlanetShocking Robots That Exist And Function Very Similar To HumansYou’ve Only Seen Such Colorful Hairdos In A Handful Of Anime12 Flicks That Almost Ended Their Stars’ CareersThe 10 Best Secondary Education Systems In The World6 Ridiculous Health Myths That Are Actually TrueCouples Who Celebrated Their Union In A Unique, Unforgettable WayWhat Happens To Your Brain When You Play Too Much Video Games?11 Most Immersive Game To Play On Your Table Top7 Reasons Why You Might Want To Become A VegetarianCan Playing Too Many Video Games Hurt Your Body?8 Superfoods For Growing Hair Back And Stimulating Its Growth
Capitals’ suffocating pressure is frustrating Golden Knights Lights inside SMX hall flicker as Duterte rants vs Ayala, Pangilinan anew Tiu said there should have been “concussion protocol” where he shouldn’t have been allowed back to the court after he was clocked.He had been advised to seek medical attention at a hospital but only had himself checked by trainers and continued with the game.“I guess this is a lesson for myself, the league and for other athletes,” he said.Rain or Shine went on to win 96-90 that Sunday. White said he had attempted to apologize to Tiu and that it wasn’t deliberate. JBRELATED STORIES:Tiu says ‘intentional’ elbow by White like ‘getting punched by Pacquiao’PBA: Rain or Shine keeps top spot, trips Magnolia in OTChris Tiu: Lessons off the bench Volcano watch: Island fissures steaming, lake water receding Don’t miss out on the latest news and information. Winfrey details her decision to withdraw from Simmons film LATEST STORIES View comments Lacson: Calamity fund cut; where did P4 billion go? China population now over 1.4 billion as birthrate falls Jury of 7 men, 5 women selected for Weinstein rape trial Chris Tiu. Image: INQUIRER.net/Tristan TamayoChris Tiu of the Rain or Shine Elasto Painters took to Instagram to reflect on his recovery after taking an elbow to the face from GlobalPort import Malcolm White.Tiu shared on his Instagram page a picture from May 20 — the night he got hit, his lips visibly swollen and scarred from the injury — and seven days after surgery, another photo showing his face healing and nearly back to normal.ADVERTISEMENT MOST READ “It was the hardest hit on the face I’ve ever experienced causing a 1 second blackout,” he said of the 6-foot-9 cager’s blow. In an interview with INQUIRER.net after the incident, he said the hit was “clearly intentional” and that “it was like getting punched by [Manny] Pacquiao.”“My doctor, who is a plastic surgeon, said that my tooth ripped through my lip muscle so deep that only the skin was left,” he explained. “There could have been worse complications with the brain and face.”He credited his doctor, Gerald Sy for stitching him up “with minimal pain during and after.”ADVERTISEMENT Carpio hits red carpet treatment for China Coast Guard PLAY LIST 02:14Carpio hits red carpet treatment for China Coast Guard02:56NCRPO pledges to donate P3.5 million to victims of Taal eruption00:56Heavy rain brings some relief in Australia02:37Calm moments allow Taal folks some respite03:23Negosyo sa Tagaytay City, bagsak sa pag-aalboroto ng Bulkang Taal01:13Christian Standhardinger wins PBA Best Player award Jiro Manio arrested for stabbing man in Marikina Steam emission over Taal’s main crater ‘steady’ for past 24 hours Sports Related Videospowered by AdSparcRead Next Dave Chappelle donates P1 million to Taal relief operations